About $800 per person is being spent yearly on commercial weight management programs.
Although lifestyle modifications (diet and exercise) remain the safest and most effective means of achieving weight loss, the outcomes are poor. Surgical procedures forcibly induce drastic lifestyle changes and carry major medical risks and high cost. There thus remains a large, unmet need for safe, efficient, and tolerable weight-loss therapies. We are addressing this need in view of the modest success of the current solutions.